
Equivalence
and Noninferiority Procedures included in version 3.0.
For noninferiority and equivalence hypotheses it's quite common to use confidence intervals
instead of one and two onesided tests, respectively. The confidence level is then chosen to
correspond to the significance level of the test. In the following situations the sample
size can be calculated using the confidence interval approach.





Equivalence,
Confidence Interval
 Diference
of Means, tdistribution
 Ratio
of Medians, Lognormal distribution
 Difference
of Proportions, Binomial distribution
 Difference
of Paired Proportions
 Comparison
of Survival, Exponential distribution

Bioequivalence,
Twoway Crossover Design
 Test
approach
 Confidence
interval approach

Noninferiority,
Confidence Interval
 Diference
of Means, tdistribution
 Ratio
of Medians, Lognormal distribution
 Difference
of Proportions, Binomial distribution
 Difference
of Paired Proportions
 Comparison
of Survival, Exponential distribution

